The 6th International Conference on Model & Data Engineering (MEDI) will be held from 21 to 23 September 2016 in Almería, Spain. Previous MEDI events took place at Obidos/Portugal (2011), Poitiers/France (2012), Calabria/Italy (2013), Larnaca/Cyrpus (2014) and Rhodes Island/ Greece (2015). The main objective of the conference is to provide a forum for the dissemination of research accomplishments and to promote the interaction and collaboration between the models and data research communities. This international scientific event, initiated by researchers from Euro-Mediterranean countries, aims also at promoting the creation of north-south scientific networks, projects and faculty/student exchanges.